Effect of Allium sativum paste against Antimicrobial, Antioxidant and Cytotoxicity activity

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چکیده

In the present work, Allium sativum paste has been prepared and analyzed to determine their antioxidant, in vitro antibacterial, in vitro cytotoxicity and apoptosis activities. Butylated hydroxy toluene has been used as standard. Results show the highest % of inhibition in DPPH assay 97.06±0.001 and metal chelating assay 82.35±0.005 at 100μg concentration. Extracts exhibited strong antimicrobial activity against Pseudomonas aeruginosa and Klebsiella pneumoniae than against Salmonella typhi. 3(4-5-dimethyl thiazol-2-yl) -2,5diphenyl tetrazolium Bromine (MTT) assay demonstrated the inhibition of 43.18% the proliferation of the Siha cervical cancer cell in time and dose dependent manners.

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تاریخ انتشار 2016